Collagen Injections with fillers such as Radiesse can be used to fill in creases, wrinkles, and depressions in facial skin, including laugh lines, smile lines, facial wrinkles, lip creases, crow's feet, and acne scars. They can also be used to treat areas of the neck, back, and chest, or to create plumper cheeks or lips.
 
To maintain the benefits of collagen treatments, injections are usually repeated periodically. New collagen injections are recommended every three to six months depending on how quickly your body absorbs the new collagen. The time between treatments varies depending on the patient and the part of the face being treated. Collagen injections are absorbed by the body more quickly in areas with greater muscle movement.